Category: fofabvlic

Diamond Trust Bank of Kenya Limited (DTK.ke) Q32015 Interim Report

first_imgDiamond Trust Bank of Kenya Limited (DTK.ke) listed on the Nairobi Securities Exchange under the Banking sector has released it’s 2015 interim results for the third quarter.For more information about Diamond Trust Bank of Kenya Limited (DTK.ke) reports, abridged reports, interim earnings results and earnings presentations, visit the Diamond Trust Bank of Kenya Limited (DTK.ke) company page on AfricanFinancials.Document: Diamond Trust Bank of Kenya Limited (DTK.ke)  2015 interim results for the third quarter.Company ProfileDiamond Trust Bank of Kenya Limited is a financial services and insurance group providing products and services to clients in Kenya, Tanzania, Uganda and Burundi. The company offers a diverse range of products for transactional banking as well as a full service offering for mortgages, asset financing and an insurance premium finance facility. Its treasury services include spot and forward foreign exchange transactions, cross currency swaps and deals, fixed income securities, corporate bonds, fixed income securities, structured treasury products and money market products. Its trade finance services include letters of credit, documentary and clean collections, negotiation of export bills, suppliers credit financing and bank guarantees. Formerly known as Diamond Trust of Kenya, the company changed its name to Diamond Trust Bank Kenya Limited in 1997. Its head office is based in Nairobi, Kenya. Diamond Trust Bank of Kenya Limited is listed on the Nairobi Securities Exchangelast_img read more

Stock market crash: 2 cheap FTSE 100 shares I’d buy now ahead of a recovery

first_imgStock market crash: 2 cheap FTSE 100 shares I’d buy now ahead of a recovery I would like to receive emails from you about product information and offers from The Fool and its business partners. Each of these emails will provide a link to unsubscribe from future emails. More information about how The Fool collects, stores, and handles personal data is available in its Privacy Statement. Simply click below to discover how you can take advantage of this. “This Stock Could Be Like Buying Amazon in 1997” Enter Your Email Address Renowned stock-picker Mark Rogers and his analyst team at The Motley Fool UK have named 6 shares that they believe UK investors should consider buying NOW.So if you’re looking for more stock ideas to try and best position your portfolio today, then it might be a good day for you. Because we’re offering a full 33% off your first year of membership to our flagship share-tipping service, backed by our ‘no quibbles’ 30-day subscription fee refund guarantee. Click here to claim your copy now — and we’ll tell you the name of this Top US Share… free of charge! Peter Stephens | Friday, 15th May, 2020 | More on: BDEV BP center_img Our 6 ‘Best Buys Now’ Shares The stock market crash has caused many FTSE 100 shares to trade at attractive levels on a long-term view. Clearly, a recovery may (or may not) take place in the short run. But the FTSE 100’s track record suggests that it is likely to occur over the long run.As such, now could be the right time to buy a range of large-cap shares while they trade at low prices. Here are two prime examples of what appear to be high-quality businesses. They may offer long-term recovery potential following their recent price declines.5G is here – and shares of this ‘sleeping giant’ could be a great way for you to potentially profit!According to one leading industry firm, the 5G boom could create a global industry worth US$12.3 TRILLION out of thin air…And if you click here we’ll show you something that could be key to unlocking 5G’s full potential…FTSE 100 housebuilder BarrattThe 37% fall in the share price of FTSE 100 housebuilder Barratt (LSE: BDEV) could present a buying opportunity. The company recently announced that it has a strong financial position. In fact, it has £430m in cash, and access to various potential funding arrangements. It has also reduced unnecessary expenditure, as well as cancelling its dividend. That should further strengthen its financial position during a period of reduced activity for the sector.Looking ahead, the housebuilding sector is expected to gradually resume operations. Although sales of new homes may be lower in the coming months due to an uncertain economic outlook and fears about job security, factors such as low interest rates and government schemes may help to support demand for new homes over the medium term. A limited supply of new homes may also support house prices to some extent.Therefore, with a challenging period seemingly priced-in to its valuation, Barratt could offer long-term recovery potential. FTSE 100 housebuilders with solid balance sheets proved to be highly profitable investments following the last UK recession. And they could likewise deliver impressive relative total returns in the coming years as the economy gradually recovers.BPThe recent quarterly update from BP (LSE: BP) highlighted the financial strain the wider oil & gas industry is facing at the present time. The FTSE 100 company’s profit in the first quarter declined by two-thirds year-on-year, and could experience similar falls in upcoming quarters as the oil price continues to trade at a relatively low level.Despite this, BP seems to be in a strong financial position to overcome a challenging period for the wider industry. Its update stated that it has $32bn of liquidity available. It also has the capacity to cut costs and reduce its dividends, should it be necessary. Therefore, while many of its peers may experience severe financial challenges, BP may be well placed to survive a challenging 2020.The company’s share price has fallen by 40% since the start of the year. Although further declines in its valuation could be ahead should the oil price fail to rise, over the long run, the stock could prove to be a worthwhile recovery opportunity for less risk-averse investors. As such, now could be the right time to buy and hold the FTSE 100 stock for the long run. Image source: Getty Images. Peter Stephens owns shares of Barratt Developments and BP. The Motley Fool UK has no position in any of the shares mentioned. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors. I’m sure you’ll agree that’s quite the statement from Motley Fool Co-Founder Tom Gardner.But since our US analyst team first recommended shares in this unique tech stock back in 2016, the value has soared.What’s more, we firmly believe there’s still plenty of upside in its future. In fact, even throughout the current coronavirus crisis, its performance has been beating Wall St expectations.And right now, we’re giving you a chance to discover exactly what has got our analysts all fired up about this niche industry phenomenon, in our FREE special report, A Top US Share From The Motley Fool. See all posts by Peter Stephenslast_img read more

Apopka Weekly Arrest Report

first_img LEAVE A REPLY Cancel reply Share on Facebook Tweet on Twitter Save my name, email, and website in this browser for the next time I comment. Please enter your name here APD Arrest Report ~ April 25 – May 1The Apopka Police Department reported the following statistics for the week ending May 1st:Calls For Service           1562Traffic Citations               38Crash Reports                   20The Apopka Police Department reported 10 arrests for the week ending May 1st.  1 juvenile was arrested.Arrested and charged were 3 adults from Apopka, 4 adults from Orlando, 1 adult from Winter Garden, 1 adult from Ocoee, 1 juvenile from Apopka.All of the arrests are listed here:HAWKINS, JAMES ALFORD (47) of ORLANDO – Multiple charges including BurglaryTAYLOR, DAVID (35) of ORLANDO – Multiple charges including BurglaryVAZQUEZ, BLANCA L (46) of APOPKA – LarcenyALVAREZ, EDUARDO PATRICIO (19) of WINTER GARDEN – Multiple charges including Driving While License Suspended or RevokedHUNTER, DEMETRICE LAVONE (27) of ORLANDO – BatteryJOHNSON, TYRONE TRAMELL (40) of APOPKA – Multiple charges including shopliftingBORIA, HECTOR LUIS (26) of ORLANDO – Multiple charges including DUITRUONG, TONY NGUYEN (24) of OCOEE – DUISUGGS, ZANE DARYL (48) of APOPKA – Multiple charges including Aggravated AssaultJUVENILE (14) of APOPKA – BurglaryArrest report details provided by the Apopka Police Department Gov. DeSantis says new moment-of-silence law in public schools protects religious freedom UF/IFAS in Apopka will temporarily house District staff; saves almost $400,000 Please enter your comment! Florida gas prices jump 12 cents; most expensive since 2014 You have entered an incorrect email address! Please enter your email address here TAGSAPDApopka Police DepartmentArrest Report Previous articleCandidate for State House speaking at NORWFNext articleHow to make more money when you sell your home Claire Haslett RELATED ARTICLESMORE FROM AUTHORlast_img read more

Munster too good for the USA in their preseason friendly

first_imgWednesday Aug 27, 2008 Munster too good for the USA in their preseason friendly Heineken Cup champions Munster comfortably defeated a determined USA Eagles side 46-22 in a pre-season friendly played in East Hartford, Connecticut on Saturday.The USA scored first through a nice try from Justin Boyd in the corner, but Munster came back hard, scoring 17 points before the USA got a late try from Louis Stanfill, keeping them in the game with the halftime score at 20-15.The friendly was competitive througout, with Munster missing a few big name players such as Ronan O’Gara, Doug Howlett, Peter Stringer, and Paul O’Connel. The rest of the squad were strong enough though, and in the second half they extended their lead with a few nice tries, including two pushover tries, dispelling the myth that the art of the rolling maul is dead under the ELV’s.A yellow card for the US didn’t help their cause, and Munster cruised to victory with tries by Ireland internationals Frank Sheahan and Barry Murphy, both replacements, scoring a try a piece. Eagles flyhalf Nese Malifa finished with 12 points and had a good game all round, before being taken off with a shoulder injury.Munster take on London Irish this friday night ahead of their Magners League meeting at Murrayfield against Edinburgh in two weeks time. Time: 05:45ADVERTISEMENT Posted By: rugbydump Share Send Thanks Sorry there has been an error Related Articles 81 WEEKS AGO scottish prop saves fire victim 84 WEEKS AGO New Rugby X tournament insane 112 WEEKS AGO Vunipola stands by his comments supporting… From the WebThis Video Will Soon Be Banned. Watch Before It’s DeletedSecrets RevealedDoctors Stunned: This Removes Wrinkles Like Crazy! (Try Tonight)Smart Life ReportsIf You Have Ringing Ears Do This Immediately (Ends Tinnitus)Healthier Living90% of People Have No Idea What These Two Little Holes Are ForNueeyYou Won’t Believe What the World’s Most Beautiful Girl Looks Like TodayNueey10 Types of Women You Should Never MarryNueeyThe content you see here is paid for by the advertiser or content provider whose link you click on, and is recommended to you by Revcontent. As the leading platform for native advertising and content recommendation, Revcontent uses interest based targeting to select content that we think will be of particular interest to you. We encourage you to view your opt out options in Revcontent’s Privacy PolicyWant your content to appear on sites like this?Increase Your Engagement Now!Want to report this publisher’s content as misinformation?Submit a ReportGot it, thanks!Remove Content Link?Please choose a reason below:Fake NewsMisleadingNot InterestedOffensiveRepetitiveSubmitCancel ADVERTISEMENT Trending 6 DAYS AGO HUGE controversy sees Borthwick call Pat Lam a liar during heated Prem clash 5 DAYS AGO Melbourne Rebels do their best to wreck Bryn Gatland 4 DAYS AGO Lam’s explanation of bizarre situation that caused heated touchline argument 5 DAYS AGO François Steyn’s ridiculous 60-metre drop goal which left commentators in hysterics 5 DAYS AGO The time Waisale Serevi used his iconic hitch-kick to carve up Scotland in 2000 Great Tries 5 DAYS AGO Eye-opening compilation shows why Taulupe Faletau could harm Springboks this Summer 5 DAYS AGO The time Waisale Serevi used his iconic hitch-kick to carve up Scotland in 2000 1 WEEK AGO Veainu finishes superb try after octopus style offload from Waisea 2 WEEKS AGO FULL MATCH REPLAY: Huge stars on show when All Blacks host Pacific Island XV in 2004 2 WEEKS AGO WATCH: Hooker produces ridiculous speed to score 60-metre wonder try for Hurricanes View All Big Hits & Dirty Play 1 DAY AGO Awesome new Etzebeth montage will have Springboks fans psyched for Summer Lions tour 5 DAYS AGO Melbourne Rebels do their best to wreck Bryn Gatland 5 DAYS AGO Eye-opening compilation shows why Taulupe Faletau could harm Springboks this Summer 5 DAYS AGO Re-live O’Driscoll’s EPIC try-saving tackle in 2003 RWC quarter-final 1 WEEK AGO AWESOME video shows the very biggest and best tackles of the 2020/21 season View All See It To Believe It 4 DAYS AGO Cheetah racer Habana reveals what was actually going through his mind that day 4 DAYS AGO Lam’s explanation of bizarre situation that caused heated touchline argument 5 DAYS AGO François Steyn’s ridiculous 60-metre drop goal which left commentators in hysterics 5 DAYS AGO Re-live O’Driscoll’s EPIC try-saving tackle in 2003 RWC quarter-final 6 DAYS AGO HUGE controversy sees Borthwick call Pat Lam a liar during heated Prem clash View All Funnies 2 WEEKS AGO Joe Marler elated in special interview as fans return to The Stoop 2 WEEKS AGO WATCH: One of the luckiest and most bizarre tries you will EVER see 2 WEEKS AGO WATCH: Reds players caught out in hilarious celebration blooper vs Chiefs 2 WEEKS AGO WATCH: Faz, Piutau and Burns star in hilarious try fail compilation 4 WEEKS AGO MLR: Giltinis howler sees try overruled despite attempts to celebrate View All Amateur 32 WEEKS AGO Viral video of Scottish club brawl goes down a storm with rugby community 69 WEEKS AGO RUGBYDUMP BLITZ: This Best of the Week round up is sure to entertain you 69 WEEKS AGO RD BLITZ – Disaster, just when it looked so promising… 69 WEEKS AGO That glorious moment that will live on forever, like it or not 69 WEEKS AGO RD Blitz – PROP’S Lionel Messi wizardy creates incredible try View All Player Features 16 WEEKS AGO WATCH: Bumping off tacklers and taking high balls, Rob Kearney had an impressive Super Rugby debut 21 WEEKS AGO Brian Moore on money in modern rugby and how it should never be compared to ‘outlier’ football 22 WEEKS AGO Tuisova’s wrecking ball montage will make you grateful you never made it as a pro 28 WEEKS AGO New Zealand rugby pod admit Owen Farrell is world class 29 WEEKS AGO WATCH: Bath prop launches Amazon documentary focused on those from non-traditional backgrounds View All Related Content from the RugbyPass Network ‘What you do today is how you’re going to be remembered’: Spirit of Rugby – Ep 5 In Spirit of Rugby episode 5, Jim Hamilton talks Lions with Matt Dawson, Jeremy Guscott, Rob Kearney, Simon Shaw, Tom Croft and John Bentley. Watch: Reforging the Steelers | Episode 2 | RugbyPass Original Documentary In Episode 2 of Reforging the Steelers, we follow the team through rounds two to four as they try to get their season on track after an opening loss to competition powerhouses Tasman. Gavin Coombes grabs four tries as Munster easy to victory over Zebre Gavin Coombes scored four tries at Zebre as Munster secured second place in the northern section of the Guinness PRO14 Rainbow Cup. Leinster finish with Rainbow flourish as fans attend RDS for first time in 16 months Retiring duo Scott Fardy and Michael Bent bowed out on a winning note as Leinster finished the Rainbow Cup with a victory over Dragons. Final round of the Gallagher Premiership hit by a second match cancellation The final round of the Premiership lost the Worcester-Gloucester match on Tuesday and now Bristol versus London Irish is off. Crusaders player ratings vs Rebels | Super Rugby Trans-Tasman Which Crusaders stood out in their 26-point win over the Rebels in the final round of Super Rugby Trans-Tasman? Munster too good for the USA in their preseason friendly | RugbyDump – Rugby News & Videos RugbyDump Home RugbyDump Academy Store About Contact Legal Privacy Policy Cookie Policy Categories Latest Great Tries Big Hits & Dirty Play See It To Believe It Funnies Training Videos Player Features RugbyDump Home RugbyDump Academy Store About Contact Sitemap Categories Latest Great Tries Big Hits & Dirty Play See It To Believe It Funnies Training Videos Player Features Legal Privacy Policy Cookie Policy Sign In Username or Email Password Stay logged in Forgot password Thank you for registering Click here to login Register Register now for RugbyDump commenting & enewsletter. * Required fields. Username * Password * Email * Password Repeat * Please send me news, information and special offers from RugbyDump By clicking register you agree to our Privacy Policylast_img read more

House in Preguiçosas / Branco-DelRio Arquitectos

first_imgShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/793945/house-in-preguicosas-branco-delrio-arquitectos Clipboard CopyHouses•Coimbra, Portugal Photographs:  do mal o menos Construction Manager:Rodrigo SobralStructure:Em Branco, Arquitectura, Engenharia e Design GráficoMechanical Engineering:BISCARTSContractor:J.Tavares & FilhosAuthor:João BrancoCollaborators:Paula Del Río, Gerson ReiCity:CoimbraCountry:PortugalMore SpecsLess SpecsSave this picture!© do mal o menosText description provided by the architects. The house is located in the outskirts of Coimbra, an area of single family homes in consolidation process. The plot currently enjoys a pleasant view and is a bit isolated, features that will disappear when adjacent buildings rise. Thus the house, elevated as required by the rules, is enclosed seeking one single opening with a porch to the south garden.Save this picture!© do mal o menosSave this picture!© do mal o menosThe house makes up for its small size by connecting spaces. It seizes the exterior of both the garden and patio, incorporating them through the continuity of the elements. The interiors follow one another, link and relate visually. Always offering distant perspectives and specific visual relations with the outside.Save this picture!PlanSave this picture!PlanThe organization on three floors responds to the classical system of services – social areas – bedrooms, characterized by differences in light and materiality: from the cavernous basement to the overhead light that bathes the stairs and the work area adjacent to it at the top floor. The social floor is organised around the kitchen which the owners, a couple with young children, considered the centre of their activity and their house habits.Save this picture!© do mal o menosSave this picture!© do mal o menosThe two larger divisions occupy opposite ends: the south living room appropriates the garden and the studio to north closes to the street. Both connect through the courtyard, which belongs to them equally. All plans that connect these spaces are continuous and fluid, and hidden door and window frames fade limits.Save this picture!SectionThe construction of this house was made with a strict economic control and quality, aiming at the correct execution of the details thus allowing, with a very limited budget, surprising results.Save this picture!© do mal o menosProject gallerySee allShow lessWatch Prominent Architectural Lectures and More from The Architectural League of New…Architecture NewsApply to the Strelka Institute: New Educational Programme LaunchedOpportunities Share House in Preguiçosas / Branco-DelRio ArquitectosSave this projectSaveHouse in Preguiçosas / Branco-DelRio Arquitectos 2015 House in Preguiçosas / Branco-DelRio Arquitectos Year:  “COPY” “COPY” Projectscenter_img Architects: Branco-DelRio Arquitectos Year Completion year of this architecture project Houses Portugal Photographs ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/793945/house-in-preguicosas-branco-delrio-arquitectos Clipboard Save this picture!© do mal o menos+ 33 Share ArchDaily CopyAbout this officeBranco-DelRio ArquitectosOfficeFollowProductConcrete#TagsProjectsBuilt ProjectsSelected ProjectsResidential ArchitectureHousesCoimbraPortugalPublished on August 29, 2016Cite: “House in Preguiçosas / Branco-DelRio Arquitectos” [Casa das Preguiçosas / Branco-DelRio Arquitectos] 29 Aug 2016. ArchDaily. Accessed 11 Jun 2021. ISSN 0719-8884Read commentsBrowse the CatalogPanels / Prefabricated AssembliesTechnowoodPanel Façade SystemRailing / BalustradesMitrexIntegrated Photovoltaic Railing – BIPV RailingMetal PanelsAurubisPatinated Copper: Nordic Green/Blue/Turquoise/SpecialPlastics / FibersRodecaTranslucent Building Elements in Downton Primary SchoolSkylightsVELUX CommercialModular Skylights – LonglightBathroom FurnitureBradley Corporation USAToilet Partition CubiclesSignage / Display SystemsGoppionDisplay Case – One-offAcousticFabriTRAK®FabriFELT™ for Walls and CeilingsBoardsStructureCraftStructural Panel – Dowel Laminated TimberThermalSchöckInsulation – Isokorb® Concrete to SteelDoorsJansenSmoke Control Door – Economy 60Louvers / ShuttersShade FactorExternal Venetian BlindsMore products »Read commentsSave想阅读文章的中文版本吗?Casa das Preguiçosas / Branco-DelRio Arquitectos是否翻译成中文现有为你所在地区特制的网站?想浏览ArchDaily中国吗?Take me there »✖You’ve started following your first account!Did you know?You’ll now receive updates based on what you follow! Personalize your stream and start following your favorite authors, offices and users.Go to my streamlast_img read more

Government call centres help handle Comic Relief donation calls

first_img  30 total views,  1 views today AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to LinkedInLinkedInShare to EmailEmailShare to WhatsAppWhatsAppShare to MessengerMessengerShare to MoreAddThis Advertisement Fourteen DWP call centres will take part in the Comic relief fundraising event on Friday after staff expressed their interest in contributing to the annual charity campaign.An estimated 1,400 people will give up their spare time to take public donations from the call centres on March 11 in the non-stop seven hour phone-in. Call centres from Jobcentre Plus, The Pension Service and the Disability and Carers service helplines will all be contributing their ‘out of office hours’ service for free in a bid to raise record amounts for the Red Nose Day 10th anniversary. Tagged with: Digital Events Recruitment / people About Howard Lake Howard Lake is a digital fundraising entrepreneur. Publisher of UK Fundraising, the world’s first web resource for professional fundraisers, since 1994. Trainer and consultant in digital fundraising. Founder of Fundraising Camp and co-founder of GoodJobs.org.uk. Researching massive growth in giving.center_img Howard Lake | 9 March 2005 | News AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to LinkedInLinkedInShare to EmailEmailShare to WhatsAppWhatsAppShare to MessengerMessengerShare to MoreAddThis Government call centres help handle Comic Relief donation callslast_img read more

Santander Consumer: 4Q Earnings Snapshot

first_imgLocal NewsBusinessState Twitter By Digital AIM Web Support – February 3, 2021 Pinterest WhatsApp Twitter Facebook Facebookcenter_img Pinterest DALLAS (AP) — Santander Consumer USA Holdings Inc. (SC) on Wednesday reported fourth-quarter earnings of $521.5 million. On a per-share basis, the Dallas-based company said it had profit of $1.70. The results surpassed Wall Street expectations. The average estimate of five analysts surveyed by Zacks Investment Research was for earnings of $1.13 per share. The consumer finance company posted revenue of $2.06 billion in the period, also surpassing Street forecasts. Three analysts surveyed by Zacks expected $2.03 billion. For the year, the company reported profit of $910.9 million, or $2.87 per share. Revenue was reported as $8.09 billion. Santander Consumer shares have risen slightly more than 7% since the beginning of the year. The stock has dropped 11% in the last 12 months. ————— This story was generated by Automated Insights (http://automatedinsights.com/ap) using data from Zacks Investment Research. Access a Zacks stock report on SC at https://www.zacks.com/ap/SC WhatsApp Santander Consumer: 4Q Earnings Snapshot TAGS  Previous articleCapri Holdings Limited Announces Third Quarter Fiscal 2021 ResultsNext articleAtlético forward João Félix tests positive for COVID-19 Digital AIM Web Supportlast_img read more

BMW and quad seized by Buncrana RPU

first_imgHomepage BannerNews A BMW and a quad have been seized by Buncrana Roads Policing Unit.Upon stopping the BMW SUV driver yesterday, Gardai established that the driver was disqualified, had no insurance or driving licence.The quad was stopped at same location and the driver also found to have no insurance.Gardai say proceedings are to follow. Community Enhancement Programme open for applications Facebook WhatsApp Arranmore progress and potential flagged as population grows Nine til Noon Show – Listen back to Monday’s Programme Pinterest News, Sport and Obituaries on Monday May 24th Twitter Google+ By News Highland – August 30, 2019 center_img BMW and quad seized by Buncrana RPU Important message for people attending LUH’s INR clinic Twitter Loganair’s new Derry – Liverpool air service takes off from CODA RELATED ARTICLESMORE FROM AUTHOR WhatsApp Google+ Previous articlePARC welcomes RSA u-turn on additional learner permitsNext articleTonight’s Finn Harps and St Patrick’s Athletic game postponed News Highland Pinterest Facebooklast_img read more

Deadly opioid ‘ISO’ implicated in at least 19 overdoses in US after China bans fentanyl

first_imgBackyardProduction/iStockBy DR. HEATHER J. KAGAN, ABC News(NEW YORK) — A deadly and potent opioid, nicknamed “ISO,” first hit the illicit drug market in the United States last year, and since August 2019 has taken the lives of at least 19 Americans, alarming addiction experts and prompting the Drug Enforcement Administration (DEA) to take action. Most of the deaths occurred in the Midwest, but ISO has also appeared in Canada and Europe.ISO, short for Isotonitazene, “is a white or yellow powder [that] can be mixed with other substances,” said Dr. Roueen Rafeyan, the chief medical officer of the Gateway Foundation and an assistant professor of psychiatry at Northwestern University.It’s a manufactured opioid, also called a “synthetic opioid,” similar to fentanyl but estimated to be even more potent, Rafeyan said. “In humans, it is probably 60 times stronger than morphine,” he added.Since the dawn of the opioid epidemic, doctors and law enforcement officials have been grappling with wave after wave of new illicit substances. First, it was prescription painkillers. Then, when legislative change made those more difficult to traffic, the market turned to back to heroin, and later, the much more potent synthetic fentanyl.Now, experts are concerned ISO might be the newest dangerous illegal opioid claiming lives. ISO has actually been around since the 1950s, but was not thought to be particularly threatening to human health — until now. It wasn’t until June of this year that the DEA first categorized it as a “schedule I” drug, meaning that it has “no currently accepted medical use and a high potential for abuse,” like heroin.“[It] went under the radar,” said Dr. Harshal Kirane, the medical director of Wellbridge Addiction Treatment and Research.It’s a derivative of etonitazene, a synthetic opioid first developed by pharmaceutical companies to treat pain, “but because it was really strong and had side effects, it really never gained medical use,” Rafeyan explained.So why is ISO suddenly making a devastating appearance?“One of the primary reasons ISO in particular has resurfaced now is that China banned fentanyl and all of its derivatives in 2019,” Kirane said. Because fentanyl was suddenly less available, manufacturers started producing other synthetic opioids to meet demand, he explained.As the new kid on the block, ISO was also able “to evade regulation,” said Dr. Rebecca Trotzky-Sirr, an assistant professor of clinical emergency medicine at University of Southern California and the medical director of jail health services at LAC+USC. In other words, manufacturing, distributing, possessing and using ISO wasn’t illegal until the DEA made it a schedule I drug.But regulation isn’t the only thing ISO has successfully evaded — it’s also been deceiving clinicians and people who struggle with substance use.“Routine tests don’t pick it up,” and while 19 people were identified as dying of ISO overdoses, this is probably and underestimate, Rafeyan said. ISO was only linked to the 19 deaths after those bodies underwent autopsies.Rafeyan described a particularly worrisome cluster of cases with devastating consequences due to ISO’s invisibility, where “known cocaine users [bought] cocaine, used it, overdosed and died, and they thought that it was maybe laced with fentanyl, but actually the cases are turning out to be ISO.”Amid the coronavirus pandemic, Trotzky-Sirr said, “We see that people are going to different suppliers for their drugs and there’s just more unknown.”Gateway Foundation, the largest non-profit substance use treatment center in the country, is actively developing a urine drug test that will detect ISO, aimed to provide results “within a couple of hours,” Rafeyan said.He also emphasized the importance of rapid testing for getting people who have overdosed on ISO life-saving treatment. A medication called Naloxone, also known as Narcan, reverses the effects of opioids and can prevent death from an overdose if administered quickly.“There are some reports that actually Narcan does work for [ISO], but you need higher doses and repeated dosing,” Rafeyan said. Testing for ISO will avoid situations where a patient who has used ISO is given a standard amount of Naloxone “and it doesn’t work, and the providers and doctors start thinking maybe this is something else,” missing an opportunity to save a life.Naloxone comes in a nasal spray that can be administered by the public to anyone suspected of having overdosed on an opioid.Overall, Kirane said, “ISO represents the next step in this ongoing cycle of more readily available, more potent synthetic opioids.”So, what we can do about it? Getting the word out and making Naloxone accessible are two good places to start.“It is really important for everyone to be aware of [ISO] — the health care community, as well as the general population,” Rafeyan said.Trozky-Sirr said, “Naloxone should be made available and given to many of our community members and our patients.”Heather J. Kagan, M.D., is an internal medicine resident physician at The Johns Hopkins Hospital and a contributor to the ABC News Medical Unit.Copyright © 2020, ABC Audio. All rights reserved.last_img read more

Coronavirus live updates: US reports over 147,000 new cases

first_imgnarvikk/iStockBy MORGAN WINSOR, ERIN SCHUMAKER and IVAN PEREIRA, ABC News(NEW YORK) — A pandemic of the novel coronavirus has now infected more than 99.7 million people worldwide and killed over 2.1 million of them, according to real-time data compiled by the Center for Systems Science and Engineering at Johns Hopkins University.Here’s how the news is developing Tuesday. All times Eastern:Jan 26, 4:32 amUS reports over 147,000 new casesThere were 147,254 new cases of COVID-19 confirmed in the United States on Monday, according to a real-time count kept by Johns Hopkins University.Monday’s case count is far less than the country’s all-time high of 298,031 newly confirmed infections on Jan. 2, Johns Hopkins data shows.An additional 1,758 fatalities from COVID-19 were registered nationwide on Monday, down from a peak of 4,462 new deaths on Jan. 12, according to Johns Hopkins data.COVID-19 data may be skewed due to possible lags in reporting over the Martin Luther King Jr. Day holiday weekend.A total of 25,297,072 people in the U.S. have been diagnosed with COVID-19 since the pandemic began, and at least 421,129 have died, according to Johns Hopkins data. The cases include people from all 50 U.S. states, Washington, D.C., and other U.S. territories as well as repatriated citizens.Much of the country was under lockdown by the end of March as the first wave of the pandemic hit. By May 20, all U.S. states had begun lifting stay-at-home orders and other restrictions put in place to curb the spread of the novel coronavirus. The day-to-day increase in the country’s cases then hovered around 20,000 for a couple of weeks before shooting back up over the summer.The numbers lingered around 40,000 to 50,000 from mid-August through early October before surging again to record levels, crossing 100,000 for the first time on Nov. 4, then reaching 200,000 on Nov. 27 before nearing 300,000 on Jan. 2.So far, the U.S. Food and Drug Administration has authorized two COVID-19 vaccines for emergency use — one developed by U.S. pharmaceutical giant Pfizer and its German partner BioNTech, and another developed by American biotechnology company Moderna and the National Institute of Allergy and Infectious Diseases.Copyright © 2021, ABC Audio. All rights reserved.last_img read more