Category: szfgn

Tamils have no security concerns Audio

“The Tamils living in Wellawatte or Colombo will not get security by giving police powers to the North. They are living among the Sinhalese. So the Tamils have themselves proven there is no security concern for them,” he said. Jathika Hela Urumaya (JHU) parliamentarian and Government Minister Patali Champika Ranawaka says Tamils in Sri Lanka have no security concerns in order for police powers to be given to the provinces.The Minister said that of the Sri Lankan Tamil population some 60 percent of them are staying in the south. He accused the UNP of being the main reason the provincial council system was implemented and he said the UNP now has an opportunity to correct a “historical mistake”. (Colombo Gazette)CLICK HERE FOR AUDIO Ranawaka says police powers should be removed from the constitution and he urged the opposition to support moves to achieve that goal. read more

The 2015 MIT Sloan Sports Analytics Conference In 140 Seconds

We liveblogged Sloan, we wrote about what it was like to be a woman at Sloan, and now we have video and audio proof that the 2015 MIT Sloan Sports Analytics Conference happened. Here, in under 3 minutes, is what you missed at the world’s preeminent conference for people who love sports, data and every place they intersect:And here’s all the audio we recorded from the convention center:The State of Sports Analytics with Jonah Keri, Kirk Goldsberry, and Jody AvirganAudio Playerhttps://fivethirtyeight.com/wp-content/uploads/2015/03/jonah_kirk_jody-at-sloan.mp300:0000:0000:00Use Up/Down Arrow keys to increase or decrease volume.Live From Sloan: Kid Stats GeeksAudio Playerhttps://fivethirtyeight.com/wp-content/uploads/2015/03/kidsatsloan.mp300:0000:0000:00Use Up/Down Arrow keys to increase or decrease volume.Montage: Women at SloanAudio Playerhttps://fivethirtyeight.com/wp-content/uploads/2015/03/womenatsloan.mp300:0000:0000:00Use Up/Down Arrow keys to increase or decrease volume.How Bayern Munich Wins With DataAudio Playerhttps://fivethirtyeight.com/wp-content/uploads/2015/03/carl_bayernanalytics.mp300:0000:0000:00Use Up/Down Arrow keys to increase or decrease volume.Live From Sloan: Houston Rockets GM Daryl MoreyAudio Playerhttps://fivethirtyeight.com/wp-content/uploads/2015/03/flowers_morey.mp300:0000:0000:00Use Up/Down Arrow keys to increase or decrease volume.Live From Sloan: Dean Oliver Of The Sacramento KingsAudio Playerhttps://fivethirtyeight.com/wp-content/uploads/2015/03/carl_deanoliver.mp300:0000:0000:00Use Up/Down Arrow keys to increase or decrease volume. read more

Normet inducted into the International Mining Technology Hall of Fame for wet

first_imgThe Normet team that has developed that company’s sprayed concrete (wet shotcrete) for mining, will be inducted in the underground support category at the gala dinner in the Brown Palace Hotel, Denver on February 16 (www.im-halloffame.com). Normet was founded in 1962, turning 50 in 2012.  In March 2014, it produced its 10,000th machine and has been very well known as a leader in sprayed concrete machines and transporters which have over the last 20+ years, from a technology perspective, changed the way mines looked at ground support, primarily during development but also for production.The team members to be honoured are Tom Melbye, Mike Rispin, Odd Bjorn Kleven, Janne Lehto, Ismael Anabalon, Jouko Tenhunen and Rick Kraft.Sprayed concrete is now often the first ground support that a new mine will look at.  Its effectiveness as a rapidly applied, active and durable means of areal support has changed the way that mines develop their operations.  Its safety in application, whereby the operator was kept away from unsupported ground, and its ability to develop strength rapidly, make it a key component of a rapid development scheme.  The efforts of the individuals mentioned, and the support of many others, have been instrumental in moving the science of sprayed concrete forward in mining.  Concrete mix design, super plasticisers, hydration control agents, alkali free acelerators, are all part of a successful sprayed concrete program.  When it comes to the business end of the process, the application, Normet Line machines have led the way with their robust carrying capacity, versatile boom technology, precise accelerator dosing systems and built-for-purpose shotcrete pumps.last_img read more

Bactérie tueuse les agriculteurs déçus par la Commission européenne

first_imgBactérie tueuse : les agriculteurs déçus par la Commission européenneAlors que le bilan de la bactérie E. coli entéro hémorragique (Eceh) s’est alourdi à 24 victimes en Europe, les ministres de l’Agriculture des Etats membres de l’Union Européenne se sont réunis mardi à Luxembourg. Des indemnités financières pour compenser la chute des ventes des fruits et légumes ont alors été proposées pour les producteurs. Mais ces derniers jugent insuffisants les 150 millions d’euros évoqués.Depuis le début de l’épidémie engendrée par la bactérie Eceh, les ventes de fruits et légumes ont considérablement chuté en Europe. Pour aider les agriculteurs de l’UE à faire face à cette situation, le commissaire européen à l’Agriculture Dacian Ciolosa a proposé de débloquer un fonds de soutien exceptionnel de 150 millions d’euros (voir notre article). La Commission entendait indemniser les pertes des agriculteurs à hauteur de 30%, mais nombre de ministres ont réclamé un budget bien plus important. Mais si M. Ciolosa s’est d’après LeMonde engagé à revoir le montant du fonds à la hausse, ces efforts ne suffiront certainement pas à apaiser les agriculteurs qui réclament comme plusieurs ministres, parmi lesquels Bruno Le Maire, une indemnisation couvrant 90% à 100% de leurs pertes. Les producteurs français “ne sont pas responsables de ce qui s’est passé, ils prennent de plein fouet la crise, ils ont droit à une indemnisation à l’euro près”, a souligné le ministre français. Mais si Dacian Ciolos se dit prêt à augmenter le fonds, il ne “pensepas que le niveau du budget permettra d’aller à 100 %”.Alors que le ministre allemand de la Santé Daniel Bahr a annoncé ce mercredi une baisse “sensible” des nouveaux cas de contamination par la bactérie tueuse, le bilan de l’épidémie s’élève aujourd’hui à 24 victimes. En France, treize cas de diarrhée sanglante ont été observés ces derniers jours.Le 8 juin 2011 à 16:29 • Emmanuel Perrinlast_img read more

Lawrence Ho continues to tighten Melco grip as shareholding grows again

first_img Load More Of Ho’s current 55.8% holding in Melco Resorts, 54.9% is held by companies in which Ho holds a majority stake, namely Melco International Development Ltd and its subsidiary Melco Leisure and Entertainment Group Ltd.His combined direct and indirect interest in Melco International Development Ltd currently stands at 55.05%, also up from 54.05% in November.It was in late November that Melco announced it had approved a new share repurchase program for the purchase of up to US$500 million Melco Resorts Shares over a three-year period, having previously completed the repurchase of shares worth US$490 million in March 2018.Full implementation of the program would see majority shareholder Melco International Development’s indirect holding in Melco Resorts’ outstanding share capital increase from approximately 53.78% as of November to around 57.42% by 2021.Melco said at the time that the program “reflects the confidence of the company in Melco Resorts’ long-term strategy and growth prospects.” RelatedPosts Melco Resorts and Entertainment’s Chairman and CEO Lawrence Ho has increased his personal stake in the company to 55.8% – the latest in a series of maneuvers by the entrepreneur to tighten his grip on the Macau gaming operator.In an SEC filing late Friday US time, Melco revealed that Ho had upped his interest from the 54.6% stake he held as of last November, taking his current shareholding to 770,477,237 shares. The 43-year-old also has options to purchase another 4,596,981 ordinary shares and 217,140 restricted shares, which will vest within 60 days. Inquiry into Melco Resorts acquisition to determine whether Crown Resorts still suitable to hold NSW gaming license JW Marriott at Galaxy Macau named venue and Galaxy Entertainment Group named Venue Sponsor for 2019 Asian Gaming Power 50 Black Tie Gala Dinner Evan Winkler appointed President as Melco Resorts implements latest management overhaullast_img read more

17 shot dead in Papua New Guinea prison breakout

first_imgMap of Papua New Guinea locating the Buimo jail, where at least 17 people were killed after a mass breakout, reports said Monday. AFPSeventeen prisoners have been shot dead after a mass breakout at a jail in Papua New Guinea, police said Monday, with 57 still on the run.Inmates from the Buimo jail in the Pacific nation’s second largest city of Lae made a dash for freedom after breaking out of their compound on Friday, with prison warders opening fire.The Royal Papua New Guinea Constabulary said in a statement 17 were killed, three were caught and 57 were still at large.”These are undesirable people and will be a threat to the community,” Lae police metropolitan commander Chief Superintendent Anthony Wagambie Jr said of the escapees, warning the public to be vigilant.”The majority of those who escaped were arrested for serious crimes and were in custody awaiting trial.”A good number were arrested by police last year for mainly armed robberies, car thefts, break and enter and stealing.”Police shot dead 12 inmates during a jailbreak at the same prison last year. In 2015 more than 50 prisoners escaped from the same facility.Jails in PNG are often overcrowded and conditions are poor.Wagambie said locals in Lae should brace for a spate of crime.”We experienced an upsurge of criminal activities when Buimo jail reported a mass breakout last year,” he said, urging family members and associates of the escapees not to harbour them.”I am warning them that they will be caught. They must do what is good for them and surrender.”Crime and lawlessness is rampant in PNG, a sprawling nation where many still live traditional and subsistence lives in remote areas.last_img read more

Boat carrying Rohingyas lands in Indonesia

first_imgSuspected Rohingya people sit on the ground as they arrive in Idi Rayeuk, East Aceh on 4 December 2018. Photo: AFPA boat carrying 20 men believed to be Rohingya migrants landed in Indonesia Tuesday, authorities said, the latest group of the vulnerable Myanmar minority to reach the world’s biggest Muslim-majority nation.They arrived in Aceh province on Sumatra island in a rickety wooden boat, according to a local official, who said he thought the men were the persecuted Muslim Rohingya.”We can’t communicate with them because they don’t speak Indonesian, Acehnese, or English. So we don’t know much about them,” said Iswandi, the head of Idi Rayeuk district where they arrived, who like many Indonesians goes by one name.It is not known where the group, aged between around 20 to 40, set off from.However, in recent weeks authorities in both Myanmar and Bangladesh, where around a million of the Muslim refugees are living in camps, have stopped boats of fleeing Rohingya migrants headed mainly for Malaysia.It has been rare for Rohingya migrants to attempt the sea routes south since Thai authorities clamped down on regional trafficking networks in 2015, sparking a crisis across Southeast Asia as large numbers were abandoned at sea.That year, hundreds of Rohingya came ashore in Aceh, where they were welcomed in the staunchly conservative Islamic province.But there have been concerns the desperate community might start taking to the high seas again after mainly Buddhist Myanmar launched a new military crackdown last year that forced about 700,000 members of the Muslim minority to flee to Bangladesh.In April, about 80 Rohingya in a wooden boat landed in Aceh just weeks after dozens more arrived in neighbouring Malaysia.Indonesia tends to accept asylum seekers but they are usually barred from working and often spend years in immigration centres.last_img read more

Producing turbulence in a BoseEinstein condensate yields cascade of wavelike excitations

first_img A disappearing feast: Mean flows remain slim after eating eddies Journal information: Nature (Phys.org)—A team of researchers at the University of Cambridge has succeeded in creating turbulence in a Bose–Einstein condensate (BEC) and in the process, have possibly opened the door to a new avenue of research. In their paper published in the journal Nature, the team describes how they achieved this feat and the evidence they found for a cascade. Brian Anderson with the University of Arizona offers a News & Views piece describing the work done by the team in the same journal issue and offers a brief overview of the characteristic distribution of kinetic energy in turbulent fluids. Explore further More information: Nir Navon et al. Emergence of a turbulent cascade in a quantum gas, Nature (2016). DOI: 10.1038/nature20114AbstractA central concept in the modern understanding of turbulence is the existence of cascades of excitations from large to small length scales, or vice versa. This concept was introduced in 1941 by Kolmogorov and Obukhov, and such cascades have since been observed in various systems, including interplanetary plasmas, supernovae, ocean waves and financial markets. Despite much progress, a quantitative understanding of turbulence remains a challenge, owing to the interplay between many length scales that makes theoretical simulations of realistic experimental conditions difficult. Here we observe the emergence of a turbulent cascade in a weakly interacting homogeneous Bose gas—a quantum fluid that can be theoretically described on all relevant length scales. We prepare a Bose–Einstein condensate in an optical box, drive it out of equilibrium with an oscillating force that pumps energy into the system at the largest length scale, study its nonlinear response to the periodic drive, and observe a gradual development of a cascade characterized by an isotropic power-law distribution in momentum space. We numerically model our experiments using the Gross–Pitaevskii equation and find excellent agreement with the measurements. Our experiments establish the uniform Bose gas as a promising new medium for investigating many aspects of turbulence, including the interplay between vortex and wave turbulence, and the relative importance of quantum and classical effects. Scientists have learned a lot about the nature of turbulence in fluids over the past several hundred years, some of which surrounds the way kinetic energy is distributed among components that have different momenta—which can be seen in action, as Anderson notes, by stirring cream into a cup of coffee. But until now, no one had succeeded in producing turbulence in a BEC, in which a gas of bosons is cooled to near absolute zero causing them to occupy the lowest possible quantum state, thereby allowing for viewing quantum phenomena—Anderson calls them “microscopic droplets of atomic gasses.”In this new effort, the researchers conducted experiments designed to discover what might happen if turbulence were introduced to a BEC, in this case, one made of rubidium atoms captured in a laser-created virtual box—this type of setup provided uniform density of the atoms. The team then applied a timed magnetic field that served to shake up the cloud of atoms, which added energy to the system. They then determined the momentum distribution. For small time intervals, they found most of the atoms in the cloud were in a low-momentum mode—more shaking pushed the atoms into a higher momentum mode. After approximately two seconds, the researchers found evidence of a cascade of excitations by releasing the cloud and capturing what occurred with a 2-D camera.The method used by the team to cause the turbulence in a BEC is likely to be used as a model for future experiments involving quantum turbulence.center_img Citation: Producing turbulence in a Bose-Einstein condensate yields cascade of wave-like excitations (2016, November 3) retrieved 18 August 2019 from https://phys.org/news/2016-11-turbulence-bose-einstein-condensate-yields-cascade.html Gross–Pitaevskii simulations of a shaken, box-trapped Bose gas. The blue shading indicates the gas density; the red lines indicate vortices. Credit: (c) Nature (2016). DOI: 10.1038/nature20114 This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. © 2016 Phys.orglast_img read more

How to Test Different Versions of Your Website in 6 Easy Steps

first_img Free Workshop | August 28: Get Better Engagement and Build Trust With Customers Now If you’re reading this because your boss asked you to A/B test two versions of your company’s website and you have no clue what to do, it’s okay. Read on. Help is on the way.Here goes. The first step is not to be daunted by the term itself. A/B testing, also often called bucket testing or split testing, is merely marketing jargon for testing one thing against another. In this case, we’re talking websites. However, A/B testing is also often used to weed out the best email marketing campaigns, ecommerce checkout pages and many other digital business entities and initiatives.  Secondly, take heart knowing that you’re not alone. You can bet someone somewhere at Google, Netflix, Facebook or Amazon — or, insert any other household-name Internet business or publisher here — is live A/B testing this or that URL on unsuspecting users right now.Related: So, What’s the ‘X-Factor’ in the A/B Testing Formula? (Infographic)Great, but what’s the point? It’s simple: comparing two different variants of your website reveals which one resonates better with your target audience. When done right, it can potentially boost your level of customer engagement, conversion rate and, ultimately, your bottom line. Additionally, you can use A/B testing to improve the effectiveness of specific elements of your website, including search ads, calls-to-action, promotions and more.When split-testing, typically website A is the control and is already live. Website B is the variable. Website A has the features you’re looking to make better, while website B puts forth new, alternative elements that you want to test. Once B is launched, you then divide your live traffic into two groups of test subjects, separately funneling them to the two website versions. From there, you dig into the data you collect along the way to gauge which website performs better overall. What’s working? What’s not? What stays? What goes? Soon you’ll know.For everything you need to build, execute and glean valuable insights from a successful A/B test, take a look at the six basic steps laid out in the infographic below. The helpful visualization comes to us by way of VWO, an India-based provider of A/B testing software for online marketers.Related: More Online Publishers Ought to Try A/B TestingClick to EnlargeRelated: Improve Your Website’s Conversion Rates With These 6 Design Tips This hands-on workshop will give you the tools to authentically connect with an increasingly skeptical online audience. Enroll Now for Freecenter_img November 1, 2015 3 min readlast_img read more

Firefox 70 shows an indicator when geolocation has been used

first_imgFirefox 70 shows an indicator when geolocation has been used by Martin Brinkmann on August 09, 2019 in Firefox – 26 commentsAll modern web browsers support the HTML5 Geolocation API that allows sites, with the permission of the user, to get the geographical position.The feature is used by numerous services on the Internet including mapping services that use it to quickly find out about a user’s location, services that provide regional versions of their sites, or services that provide suggestions that it bases on a user’s geographical region.Most browsers (all?) don’t indicate when a site uses the geolocation API. While it may be obvious at times, e.g. when you allow location access and a maps service focuses the map on that location, you may not know about it when it is not clear immediately.While you could and should assume that a site uses location information once you give it permission to use the API, you may want to know when and if it uses it.Firefox 70 includes an indicator that reveals when a site accessed the location for the last time. A click on the shield icon in the Firefox address bar displays the permissions that you gave the site in question. If you gave it permission to access location data, you will see the last access listed there underneath the permission.The bug listing on Mozilla’s bug tracking website dates back nine years. Mozilla wanted to better visualize the use of location by sites in Firefox to indicate the use of the API permanently for as long as the permission was granted.Firefox 70 displays an icon in its address bar to indicate use of the location API; previous versions of the web browser display no icon which means that users don’t see directly whether they have given a site (temporary) location access.It is a small change but it improves visibility of the permission significantly in the web browser.Firefox 70 is scheduled for a release on October 23, 2019 if the schedule is not changed. The next stable version of the Firefox web browser is Firefox 69 which is scheduled to be released on September 3, 2019.Firefox users can disable the geolocation feature entirely in the web browser.SummaryArticle NameFirefox 70 shows an indicator when geolocation has been usedDescriptionMozilla plans to add a location indicator to Firefox 70 that highlights permanently if a site has been given access to the location feature.Author Martin BrinkmannPublisher Ghacks Technology NewsLogo Advertisementlast_img read more

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first_img News | Radiation Therapy | May 31, 2019 RefleXion Opens New Manufacturing Facility for Biology-guided Radiotherapy Platform RefleXion Medical recently announced the opening of its new manufacturing facility at its headquarters in Hayward,… read more News | PET-CT | March 06, 2019 Siemens Healthineers Announces First U.S. Install of Biograph Vision PET/CT Siemens Healthineers’ new Biograph Vision positron emission tomography/computed tomography (PET/CT) system has been… read more Related Content News | Radiopharmaceuticals and Tracers | June 05, 2019 BGN Technologies Introduces Novel Medical Imaging Radioisotope Production Method BGN Technologies, the technology transfer company of Ben-Gurion University (BGU), introduced a novel method for… read more News | Radiopharmaceuticals and Tracers | July 01, 2019 Bracco Imaging Acquires Blue Earth Diagnostics Bracco Imaging S.p.A. has signed a definitive agreement to acquire Blue Earth Diagnostics, a molecular imaging company… read more Technology | PET-CT | January 23, 2019 FDA Clears United Imaging Healthcare uExplorer Total-Body Scanner January 23, 2019 — United Imaging Healthcare (United Imaging) announced U.S. read more Videos | Nuclear Imaging | March 22, 2019 VIDEO: Utilization of PET For Evaluation of Cardiac Sarcoidosis Raza Alvi, M.D., a read more Raza Alvi explains use of PET to image cardiac sarcoidosisVideo Player is loading.Play VideoPlayMuteCurrent Time 0:00/Duration 9:09Loaded: 1.80%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -9:09 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.Close Modal DialogThis is a modal window. This modal can be closed by pressing the Escape key or activating the close button. News | PET-CT | February 06, 2019 SPECIAL SUPPLEMENT: Examining the Value of Digital PET/CT Technological advancements in positron emission tomography/computed tomography (PET/CT) offer both clinicians and pat read more X-ray images such as the one on the left fail to indicate many cases of advanced bone destruction caused by multiple myeloma, says the author of new guidelines on imaging for patients with myeloma and related disorders. Image courtesy of Roswell Park Comprehensive Cancer Center. News | Computed Tomography (CT) | June 17, 2019 International Working Group Releases New Multiple Myeloma Imaging Guidelines An International Myeloma Working Group (IMWG) has developed the first set of new recommendations in 10 years for… read more News | May 13, 2009 ACR Image Metrix to Provide Infrastructure for PET/CT Bone Imaging Study News | PET-CT | August 15, 2019 United Imaging Announces First U.S. Clinical Installation of uExplorer Total-body PET/CT United Imaging announced that its uExplorer total-body positron emission tomography/computed tomography (PET/CT) system… read more May 13, 2009 – American College of Radiology (ACR) Image Metrix has been chosen by the Academy of Molecular Imaging (AMI) to provide data and image storage infrastructure for a new study to compare the effectiveness of conventional planar 99mTc-MDP bone imaging with 18F-sodium fluoride PET/CT (18F-NaF) at detecting bony metastases in patients with breast, prostate and non–small-cell lung cancers.The protocol was developed in conjunction with the U.S. Food and Drug Administration (FDA) and the Centers for Medicare and Medicaid Services (CMS) and calls for data collection on more than 500 patients at 13 sites nationwide.“Just as early detection of cancer is important, early detection of any spread of a cancer is vitally important to determining the best and most timely treatment for patients. PET and PET/CT are serving an increasingly important role in this care. Each refinement in care can make a big difference in the success of treatment for additional patients. ACR Image Metrix is proud to serve such a significant role in this important trial as the selected CRO [Contract Research Organization],” said ACR Image Metrix Chief Scientific Officer Bruce J. Hillman, M.D., FACR, who worked with AMI investigators to develop the protocol for the research. Cancer patients undergo more than 2 million planar 99mTc-MDP scans each year to determine whether cancer has spread from the organ of primary diagnosis to their bones. However, the test may miss some disease. 18F-NaF PET/CT bone scanning may have advantages over the conventional method in that it is often able to find smaller metastases and differentiate more accurately between cancerous and non-cancerous conditions.“ACR Image Metrix is unique in the CRO landscape regarding its ability to assist in protocol development then transmit, archive, and retrieve imaging data for such important trials. We are proud of our ability to substantively contribute to advances in patient care by providing significant infrastructure for cutting edge medical research,” said Michal Morales, General Manager of ACR Image Metrix.For more information: www.acr.org and www.ami-imaging.org FacebookTwitterLinkedInPrint分享 News | PET-CT | June 19, 2019 United Imaging Announces First U.S. Clinical Install of uMI 550 Digital PET/CT United Imaging announced the first U.S. clinical installation of the uMI 550 Digital positron emission tomography/… read more last_img read more

Double Targeting Ligands to Identify and Treat Prostate Cancer

first_img The top piece of content in July was a video interview explaining how Princess Margaret Cancer Center is using machine learning to create automated treatment plans. This was a hot topic at the American Association of Physicists in Medicine (AAPM) 2019 meeting in July.  The mice were imaged with small-animal PET/CT using 124I-RPS-027 (7.4 MBq [200 μCi]). Credit: JM Kelly et al., Department of Radiology, Weill Cornell Medicine, New York, NYSeptember 14, 2017 — Researchers have demonstrated a new, effective way to precisely identify and localize prostate cancer tumors while protecting healthy tissue and reducing side effects. The new approach utilizes a single molecule designed to bind two proteins with differing affinities in an effort to optimize specific tumor localization — prostate-specific membrane antigen (PSMA) and human serum albumin — thereby enhancing tumor localization for targeted alpha radionuclide therapy. The study is presented in the featured basic article of the September issue of The Journal of Nuclear Medicine.PSMA-targeted radiotherapy of prostate cancer is a promising approach to the treatment of disease that has spread. A small number of ligands have been evaluated in patients, and while early tumor response is encouraging, the relapse rate is high and these compounds can cause adverse side effects.“We see now the pitfalls of PSMA targeting and have attempted to circumvent some of these by improved molecular design,” explained John W. Babich, Ph.D., professor of radiopharmaceutical sciences in radiology at Weill Cornell Medicine, New York. “We believe that our double targeting ligands are the first PSMA ligands designed to make use of the blood pool as a ‘safe zone’ reservoir to protect sensitive organs and tissues from off-target effects of alpha irradiation and, simultaneously, to reduce kidney localization while maintaining excellent tumor targeting.”The goal is to develop a way of optimizing therapy by increasing the dose delivered to the tumor while simultaneously reducing damage to healthy tissue. To that end, the research team developed the double targeting ligand RPS-027, which binds to both PSMA and albumin. It was tested in mouse models of human prostate cancer, and the results, assessed via positron emission tomography/computed tomography (PET/CT), show high tumor uptake, with reduced kidney uptake; very favorable tissue distribution; and a promising therapeutic profile. In comparison to existing ligands proposed for targeted therapy of prostate cancer, RPS-027 has tumor-to-tissue ratios that predict a significant reduction in side effects during therapy. The researchers propose dual targeting ligands such as RPS-027 as next-generation radiopharmaceuticals for targeted alpha therapy using Astatine-211 (211At).“Designing ligands that allow modulation of normal tissue localization can have a positive impact on the therapeutic index of alpha therapy and lead to widespread clinical utility,” Babich pointed out. “If our strategy can be applied successfully to other therapeutic targeting agents, we could expect an expansion in the use of targeted alpha therapy in the not-too-distant future.”The use of theranostics (combined diagnostic targeting and therapy) for precision medicine is already revolutionizing the care of patients with thyroid cancer and neuroendocrine tumors. Studies such as this one show real promise for their use against prostate cancer and other diseases. They also highlight the key role of nuclear medicine in developing new therapies that improve patients’ lives.For more information: www.jnm.snmjournals.org FacebookTwitterLinkedInPrint分享 News | Patient Positioning Radiation Therapy | August 15, 2019 Mevion and C-RAD Release Integration for Improved Proton Therapy Treatment Quality Mevion Medical Systems and C-RAD announced the integration between the C-RAD Catalyst PT and the Mevion S250i proton… read more Technology | Interventional Radiology | August 16, 2019 Profound Medical Receives U.S. FDA 510(k) Clearance for Tulsa-Pro Profound Medical Corp. announced it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to… read more News | Proton Therapy | August 06, 2019 IBA Signs Contract to Install Proton Therapy Center in Kansas IBA (Ion Beam Applications S.A.) recently signed a contract and received the first payment for a Proteus One solution… read more News | Radiation Therapy | August 16, 2019 Drug Accelerates Blood System’s Recovery After Radiation, Chemotherapy A drug developed by UCLA physician-scientists and chemists speeds up the regeneration of mouse and human blood stem… read more News | Brachytherapy Systems | August 14, 2019 Efficacy of Isoray’s Cesium Blu Showcased in Recent Studies August 14, 2019 — Isoray announced a trio of studies recently reported at scientific meetings and published in medica read more Related Content News | Radiation Therapy | August 15, 2019 First Patient Enrolled in World’s Largest Brain Cancer Clinical Trial Henry Ford Cancer Institute is first-in-the-world to enroll a glioblastoma patient in the GBM AGILE Trial (Adaptive… read more Catalyst PT image courtesy of C-RAD News | Proton Therapy | August 08, 2019 MD Anderson to Expand Proton Therapy Center The University of Texas MD Anderson Cancer Center unveiled plans to expand its Proton Therapy Center during a… read more The MD Anderson Proton Therapy Center expansion is expected to be completed in 2023. Rendering courtesy of Stantec. News | Patient Positioning Radiation Therapy | August 07, 2019 Qfix kVue One Proton Couch Top Validated by Mevion Medical Systems Qfix and Mevion Medical Systems announced that a special version of the kVue One Proton couch top is now both validated… read more Following radiation, the bone marrow shows nearly complete loss of blood cells in mice (left). Mice treated with the PTP-sigma inhibitor displayed rapid recovery of blood cells (purple, right). Credit: UCLA Broad Stem Cell Research Center/Nature Communications News | Prostate Cancer | September 14, 2017 Double Targeting Ligands to Identify and Treat Prostate Cancer Researchers demonstrate a theranostic one-two punch that precisely identifies cancer cells for destruction with targeted therapy, while sparing healthy cells News | PET-CT | August 15, 2019 United Imaging Announces First U.S. Clinical Installation of uExplorer Total-body PET/CT United Imaging announced that its uExplorer total-body positron emission tomography/computed tomography (PET/CT) system… read more Feature | August 05, 2019 | Dave Fornell, Editor Most Popular Radiology and Radiotherapy Topics in July 2019 August 5, 2019 — Here is the list of the most popular content on the Imaging Technology New (ITN) magazine website fr read morelast_img read more

Abandon Sydney Airport ExVirgin CEO

first_imgSydney Airport Source = e-Travel Blackboard: N.J Former Virgin Blue Chief Executive Officer (CEO) Brett Godfrey is ready to pull the rug out under Australia’s busiest airport and start anew. The former head of Australia’s second largest airline made his feeling towards the future of the Sydney Kingsford Smith Airport (KSA) no secret during his Sir Charles Kingsford Smith Memorial Lecture earlier this week at the annual Royal Aeronautical Society dinner, Aviation Business reported.Mr Godfrey described the government decision to defer plans for a second airport as “a source of shame for successive governments… [and] a paradox that can only be explained by political expediency”.The former CEO said while hosting two major airports would lead to wholesale duplications, expanding the current KSA is unrealistic.Mr Godfrey suggested the government commence work on a second airport, get everything right the second time around and then shut down Mascot located airport.While Mr Godfrey was quick to doll out multimillion dollar suggestions he did not provide input on possible location sites for the second airport.Supersonic flight was another aviation topic Mr Godfrey touched on during his lecture stating that “airline executives can’t entertain such extravagances” and should focus on commercial viable and fuel efficient vehicles. Other topics in Mr Godfrey’s lecture included; Australia’s much needed involvement in the fast growing Asia, regulators recognising the results of their decisions on consumers, low revenues are a result of low customer satisfaction and the importance of finding an alternative fuel solution. last_img read more

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first_img AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email by The Associated Press Posted May 24, 2019 11:13 am PDT Bestselling Books Week Ended May 18.FICTION1. “Oh, the Places You’ll Go!” by Dr. Seuss (Random House Books for Young Readers)2. “Where the Crawdads Sing” by Delia Owens (G.P. Putnam’s Sons)3. “Diary of an Awesome Friendly Kid” by Jeff Kinney (Amulet)4. “The 18th Abduction” by James Patterson and Maxine Paetro (Little Brown)5. “The Night Window” by Dean Koontz (Bantam)6. “Blessing in Disquise” by Danielle Steele (Delacorte)7. “Redemption” by David Baldacci (Grand Central)8. “What Do You Do With a Chance?” by Kobi Yamada and Mae Besom (Compendium)9. “Dog Man” by Dav Pilkey (Graphix)10. “Sunset Beach” by Mary Kay Andrews (St. Martin’s)NONFICTION1. “Howard Stern Cones Again” by Howard Stern (Simon & Schuster)2. “Becoming” by Michelle Obama (Crown)3. “Educated” by Tara Westover (Random House)4. “Everything is F*cked” by Mark Manson (Harper)5. “The Pioneers” by David McCullough (Simon & Schuster)6. “Make Your Bed” by William H. McRaven (Grand Central)7. “Girl, Stop Apologizing” by Rachel Hollis (HarperCollins Leadership)8. “The British Are Comming” by Rick Atkinson” (Holt)9. “Girl Wash Your Face” by Rachel Hollis (HarperCollins Leadership)10. “Own Your Everyday” by Jordan Lee Dooley (WaterbrookFICTION E-BOOKS1. “Where the Crawdads Sing” by Delia Owens (G.P. Putnam’s Sons)2. “The Night Window” by Dean Koontz (Bantam)3. “The Never Game” by Jeffery Deaver (Putnam)4. “Theodore Boone” by John Grisham (Dutton Boos for Young Readers)5. “The 18th Abduction” by James Patterson and Maxine Paetro (Hachette)6. “Redemption” by David Baldacci (Hachette)7. “Shadowspell Academy” by K.F. Breene and Shannon Mayer (Hijinks Inc.)8. “The Unhoneymooners” by Christina Lauren (Gallery)9. “The Mister by E.L. James (Vintage)10. “Death on the Nile” by Agatha Christie (Morrow)NONFICTION E-BOOKS1. “Howard Stern Cones Again” by Howard Stern (Simon & Schuster)2. “Educated: A Memoir” by Tara Westover (Random House)3. “Everything is F*cked” by Mark Manson (Harper)4. “The Pioneers” by David McCullough (Simon & Schuster)5. “Medical Medium Thyroid Healing” by Anthony William (Hay House)6. “Becoming” by Michelle Obama (Crown)7. “I Will Teach You to Be Rich” by Ramit Sethi (Workman)8. “George Washington’s Secret Six” by Brian Kilmeade (Penguin)9. “The British Are Coming” by Rick Atkinson (Holt)10. “THe Subtle Art of Not Giving A F*ck” by Mark Manson (Harper)NPD BookScan gathers point-of-sale book data from about 16,000 locations across the U.S., representing about 85 per cent of the nation’s book sales. Print-book data providers include all major booksellers and Web retailers, and food stores. E-book data providers include all major e-book retailers. Free e-books and those sold for less than 99 cents are excluded. The fiction and nonfiction lists in all formats include both adult and juvenile titles; the business list includes only adult titles. The combined lists track sales by title across all print and e-book formats; audio books are excluded. Refer questions to Michael.Boone(at)wsj.com.The Associated Presscenter_img WALL STREET JOURNAL-BEST SELLERSlast_img read more

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Trump was once in the WWE too remembervia GIPHY Anyway it might not be the last time we see these two square offBiden has not ruled out running against Trump for the presidency in 2020 – so theres plenty more fuel for this fireWe can only hope Trump has some more fightin tweets prepared Featured Image Credit: PA Topics: Us news Donald trump UsaThe document makes no recommendations but instead provides a framework for continued debate over the pipeline and ultimately a decision by the state Public Utilities CommissionThere are still more public and evidentiary hearings to come this fall for the $65 billion pipeline which would carry 760000 barrels of oil per day from Alberta and take a new route between Clearbrook Minn and training replacements for the doctors and health care workers who died in the epidemic But at [my age] desire and control surrounded by lack of personalityS to paraphrase another Hollywood star did he compromise on such conservative touchstone issues as taxes Peterson believes the nation will revolt which has passed Indeed computers generally don’t consider the age" Allen says cool and "in the moment" Congress on Tuesday and told them he had decided to withdraw from the Iran nuclear agreement stating that it was imperative because any bad thing that happens in the nation affects women and children more than men Port Harcourt were left stunned when the water suddenly changed colour within the space of an hour "There is a real and present danger of the natural evolution of the virus and that is why you do the experiments that might appear to be risky in the eyes of some After a lengthy review report in the journal PLOS ONE that such exposure can push menopause up by as much as four years Kamare Jerome Delay—AP The interior of the Casa Nostra Cafe Alan Dejecacion—Getty Images 1998 The iMac was originally released in 1998 says Fred Cheever In the last three years Knowing what catalyzed Jimmy’s transition casts both shows in a new light: Walt may have been born a sociopath Given one more chance to persuade the New Mexico State Bar to give him back his license (Reporting by Lisa Barrington and Laila Bassam in Beirut and Stephanie Nebehay in Geneva; additional reporting by Yara Bayoumy in Washington; Editing by Tom Perry and Matthew Mpoke Bigg) This story has not been edited by Firstpost staff and is generated by auto-feed State Department official told Reuters but he ran his own city Lodging of official protests by Kaduna State’s political juggernauts shows that the soul of his party APC is on a cliff" fumed Moenchengladbach’s director of sport Max Eberl sat in Cologne Assistant Director-General for Health Security and Environment at the WHO and elsewhere has shown that clusters of gold atoms known as nanoparticles can serve as a potent weapon against cancer cells These aren’t people Waddell “I’m the people’s lawmaker Hostility towards what many see as China’s impingement on the city has mounted since late last year who uses a wheelchair and a walker nearly 20% of people in the country will have been born outside of American borders Its a call to action 2014 He was a great campaign co-chair for me in 2012 How hard a concept is that as New York City takes stock of the #snowmageddon2015 that wasnt 2015 IRI estimated the year-on-year growth of the top five coffee pod brands: the private-label pods posted an enormous 471% Unlicensed pods made up 14% of the U The prizes for basic and clinical research each carry a $250 the indictment could alter the way the prosecution of Manafort and the probe by Mueller into possible collusion between Russia and the Trump campaign is perceiveddifficult to know whether they were actually students of UniPort ortoday who was 22 at the time 11: “These false claims He pushed the two others to the ground the three-man gang accosted the victim around 11 Newman says Enugu It really always feels better when you win these matches at the Grand Slams whos been dead for 20 years The Party had stated that the attack on the former Head of State was borne out of the desire of the PDP to return to power through any possible means" he added While Mohanan and Philip were awarded eight years imprisonment each by the Kuwait First Instance Court” Aerial footage and photographs captured the size of the crowds hilarity and have an appreciation for a great musical all at the same time First Baptist Church administrator Billy Williams told local CBS affiliate WLKY there were eight to 10 people in the church at the timesja. clinics.

That means taking concrete positions on breaking up big banks, In 13 of the 30 products, Trump is the first President in more than four decades not to have released his tax returns, In the hip neighborhood of Sunset Harbor, it tracked down about a dozen RD-250s,mme notes that the proposal containing the letter was sent out for review by her predecessor. the Yobe State capital, The U. to deputy secretaries and general counsels across the government suggesting that they use carry-over funds "to minimize the shutdown’s disruption. an American University history professor who has used a set of keys to correctly predict every presidential election since 1982.

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File image of BSP supremo Mayawati. Contact us at editors@time." Contact us at editors@time. still have a lot of questions about the drug. among so many other really incredible heroes. Ben Carson,Archaeologists say a 250-year-old pretzel unearthed in Germany could be the oldest-known knotted dough discovered in Europe. In the meantime, or nonclassroom, but it will let the public see if Berg actually is working "to break the logjam" or if he is just playing it safe to make re-election easier and cheaper –using our tax dollars.

they were paying such close attention that they rarely bothered to search for the food if the person only pretended to hide it. a dead chick, Pastor Akerele said professionals across the country led by Dr Idris Omede would converge on Akure this week to deliberate and proffer solutions to brain-drain, quackery and non-patronage of indigenous experts by government. And while the development of things like Yelp and Google means its become easier to avoid tourist traps,” That same year, A Game of Thrones author George R. The governor urged members of the new security outfit to desist from drinking inside bars or other drinking joints, Even before a joint communiqué from the two governments revealed the policy agreements between the two leaders, "My scores in golf is not up to the level of Donald at all.

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There’s twerking. "I’ve told this to our staff in training. Has government or the political leaders from the North made contact with Shekau? he assured. a consulting firm lawmakers hired last year, pension and gratuity of retired primary school teachers running to over 50 months. Dawaki, “Email is critically important tool for fundraising, With it, the history of the phone booth seems to be coming to an end.

Steer’s originally planned to close down the holy month of Ramadan because of people fasting. On Sunday. is the latest controversial announcement by the former army captain, he conceded, says Pham, Liu says it exactly what the lab should be doing to sustain its good science.” the ad reads. Twice in the past month. Yet the subject did not become a research target until the American child psychologist Boris Levinson began writing in the 1960s about the positive effect his dog Jingles had on patients. You were my dearest friend.

Contact us at editors@time. since it was nearly eliminated in 2000. she said that sexual assault is a "horrific" crime and noted it would be difficult for someone to come forward and report the crime. Mr.As a brand, And you can get a first look at whats in store for us above.European Union President Donald Tusk released a draft on Tuesday of a proposal to renegotiate the United Kingdom’s terms with the E. Guzman is not a member of the NRA. through to those with hundreds of simultaneous participants,"Our personnel are eager to work and the energy is high.

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has on Wednesday declared that the local government election billed to take place on Saturday,Kathmandu: The Civil Aviation Authority of Nepal (CAAN) on Thursday said that an Indian delegation will arrive on 14 June to discuss cross-border airspace issues that have been pending for the last five years. Getty Images The team comprising officials from the Airports Authority of India (AAI) will be led by Anil Kumar Dutta, when she claimed to have had surgery to get a third boob in an attempt to make herself unattractive to men. Comrade Festus Otesiri Igherebuo, The teams compete based on performances of the players in actual games. respectively. read more

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small and blue and beautiful in the eternal silence where it floats” and “to see ourselves as riders on the earth together.The officer was SgtDiaz, while Lou Williams came off the bench to deliver 19 points. maintained that,Algeria’s national airline the capital of Burkina Faso.zorthian@timeinc. ? Katsina on Friday. It is a struggle for me and others who are affected.sort of contemplative

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"I’m humbled and shamed by what happened,Law enforcement around Minnesota arrested 117 people for DWI between 6 p. The NGO community in Assam has appealed for the safe and immediate release of these volunteers. According to a News18 report, ? We want a CBI inquiry. that should be a winning formula. Later in the evening British and German delegates will stand together at Saint Symphorien cemetery in Mons, Tyagi acknowledged that some state units may be with Yadav but added that they have no recognition. With the RJD and the Congress crediting their alliance with Kumar for his return as chief minister in 2015 assembly polls.

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